Personal profile
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Research interests
My research interests are in organic and analytical chemistry, with projects funded by industrial sponsors such as GlaxoSmithKline PLC, LGC Ltd, Innovate UK and, more recently, Haleon PLC, working on the design and synthesis of fluorogenic compounds for problem pathogen detection and method development for NMR metabolomics/2D qNMR for complex mixture characterisation and metrology.
Related documents
Education/Academic qualification
PGCertHE, Kingston University
Award Date: 1 Aug 2010
Doctorate, PhD, Organic and Supramolecular Chemistry, University of Surrey
2000 → 2004
Award Date: 31 Jul 2004
Bachelor, BSc(Hons) Chemistry, University of Surrey
1996 → 2000
Award Date: 31 Jul 2000
Keywords
- QD Chemistry
- NMR
- Organic Chemistry
- fluorogenic compounds
- MRSA
- Oral Health
- anti-cancer
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Collaborations and top research areas from the last five years
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Investigating the impact of water soluble swellable polymers on the metabolic profiles of soil organisms and microbes
Le Gresley, A. (PI) & Syeda, E. (Researcher)
1/07/25 → 29/07/28
Project: Research
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KUEL NPL contract
Le Gresley, A. (PI) & Durrant, A. (Researcher)
1/12/21 → 31/12/21
Project: Knowledge Exchange
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Development of Solid State NMR techniques to analyse Oral Health hard tissue and bacterially derived samples
Le Gresley, A. (PI) & Hassan, S. (Researcher)
1/10/22 → 30/09/26
Project: Research & KE
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Investigating the impact of water-soluble polymers on the metabolic profiles of aquatic organisms and microbes
Le Gresley, A. (PI) & Sainju, D. (Researcher)
1/11/21 → 10/11/25
Project: Research
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Applications of NMR techniques to Gum Health
Le Gresley, A. (PI) & Robertson, C. (Researcher)
29/09/20 → 31/08/21
Project: Research & KE
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Prokaryotic metabolic response to water-soluble polymers enhances oxygen drawdown in freshwater systems: a polyethylene glycol case study
Sainju, D., Bercovici, S., Lucas, R., Gresley, A. L., A․ Horton, A. & Evans, C., Jan 2026, In: Next Research. 3, 8 p., 101149.Research output: Contribution to journal › Article › peer-review
Open Access -
Assessing the effects of thermo-oxidation and naturally-occurring trace metal ions on the peroxidative susceptibilities of unrefined and refined sunflower oils: An 1H NMR-coupled chemometrics study
Ampem, G., Le Gresley, A., Grootveld, M., De Mars, S. & Naughton, D. P., Dec 2025, In: Food Research International. 221, 117493.Research output: Contribution to journal › Article › peer-review
Open Access -
Modelling of cetylpyridinium chloride availability in complex mixtures for the prediction of anti-microbial activity using diffusion ordered spectroscopy, saturation transfer difference and 1D NMR
Robertson, C., Batabyal, S., Whitworth, D., Coban, T., Smith, A., Montesanto, A., Lucas, R. & Le Gresley, A., Dec 2024, In: Pharmaceuticals. 17, 12, 1570.Research output: Contribution to journal › Article › peer-review
Open Access -
Effectiveness of different antioxidants in suppressing the evolution of thermally induced peroxidation products in hemp seed oil
Ampem, G., Le Gresley, A., Grootveld, M. & Patrick Naughton, D., Jul 2024, In: Food Research International. 188, 114415.Research output: Contribution to journal › Article › peer-review
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Using nuclear magnetic resonance to troubleshoot a stability issue in a real-world formulation chassis—application to consumer oral healthcare
Coban, T., Sykes, H., Kulkarni, S., Lucas, R. A., Robertson, C. & Le Gresley, A., Mar 2024, In: Pharmaceutics. 16, 3, 320.Research output: Contribution to journal › Article › peer-review
Open Access
Activities
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EU H2020 (External organisation)
Le Gresley, A. (Member)
31 Jan 2016Activity: Membership › Positions at funding bodies and HE policy organisations
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Jacobs University Bremen
Le Gresley, A. (Visiting researcher)
Nov 2021 → Nov 2023Activity: External academic positions › Academic honorary or visting title
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Royal Society of Chemistry (External organisation)
Le Gresley, A. (Member)
31 Mar 2018Activity: Membership › Professional memberships
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Heart Research UK (External organisation)
Le Gresley, A. (Member)
2017Activity: Membership › Positions at funding bodies and HE policy organisations
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Institut de Ciència de Materials de Barcelona (ICMAB-CSIC). (External organisation)
Le Gresley, A. (Member)
2022Activity: Membership › Positions at funding bodies and HE policy organisations