2-Nitroimidazol-5-ylmethyl as a potential bioreductively activated prodrug system: reductively triggered release of the parp inhibitor 5-bromoisoquinolinone

Ifat Parveen; Declan P. Naughton; William J. D. Whish; Michael D. Threadgill

doi:10.1016/S0960-894X(99)00306-6

2-Nitroimidazol-5-ylmethyl as a potential bioreductively activated prodrug system: reductively triggered release of the parp inhibitor 5-bromoisoquinolinone

Ifat Parveen
, Declan P. Naughton
, William J. D. Whish
, Michael D. Threadgill

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	2031-2036
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	9
Issue number	14
DOIs	https://doi.org/10.1016/S0960-894X(99)00306-6
Publication status	Published - 19 Jul 1999
Externally published	Yes

Keywords

Pharmacy

Access to Document

10.1016/S0960-894X(99)00306-6

http://dx.doi.org/doi:10.1016/S0960-894X(99)00306-6

Cite this

@article{f917184bf74548e6bd32fdce9c8d8fc0,

title = "2-Nitroimidazol-5-ylmethyl as a potential bioreductively activated prodrug system: reductively triggered release of the parp inhibitor 5-bromoisoquinolinone",

keywords = "Pharmacy",

author = "Ifat Parveen and Naughton, \{Declan P.\} and Whish, \{William J. D.\} and Threadgill, \{Michael D.\}",

year = "1999",

month = jul,

day = "19",

doi = "10.1016/S0960-894X(99)00306-6",

language = "English",

volume = "9",

pages = "2031--2036",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Ltd",

number = "14",

}

2-Nitroimidazol-5-ylmethyl as a potential bioreductively activated prodrug system: reductively triggered release of the parp inhibitor 5-bromoisoquinolinone. / Parveen, Ifat; Naughton, Declan P.; Whish, William J. D. et al.
In: Bioorganic and Medicinal Chemistry Letters, Vol. 9, No. 14, 19.07.1999, p. 2031-2036.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - 2-Nitroimidazol-5-ylmethyl as a potential bioreductively activated prodrug system

T2 - reductively triggered release of the parp inhibitor 5-bromoisoquinolinone

AU - Parveen, Ifat

AU - Naughton, Declan P.

AU - Whish, William J. D.

AU - Threadgill, Michael D.

PY - 1999/7/19

Y1 - 1999/7/19

KW - Pharmacy

U2 - 10.1016/S0960-894X(99)00306-6

DO - 10.1016/S0960-894X(99)00306-6

M3 - Article

SN - 0960-894X

VL - 9

SP - 2031

EP - 2036

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 14

ER -