A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response

Filippo Casoni; Jan Peters; Uli Bromberg; Matthew Hill; Mark Lathrop; Jean-Luc Martinot; Tomas Paus; Sylvane Desrivieres; Marcus Munafo; Marjo-Riitta Jarvelin; Gunter Schumann; Jessica Buxton; Alexandra Blakemore; Juha Veijola; Christian Buchel; Tobias Banaschewski; Arun L.W. Bokde; Yuning Zhang; Barbara Ruggeri; Tianye Jia; Marika Kaakinen; Gursharan Kalsi; Pimphen Charoen; Patricia Conrod; Herta Flor; Vincent Frouin; Jürgen Gallinat; Hugh Garavan; Penny A. Gowland; Andreas Heinz; Bernd Ittermann; Christine Macare; Francesca Ducci

doi:10.1016/j.euroneuro.2018.07.101

A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response

Filippo Casoni
, Jan Peters
, Uli Bromberg
, Matthew Hill
, Mark Lathrop
, Jean-Luc Martinot
, Tomas Paus
, Sylvane Desrivieres
, Marcus Munafo
, Marjo-Riitta Jarvelin
, Gunter Schumann
, Jessica Buxton
, Alexandra Blakemore
, Juha Veijola
, Christian Buchel
, Tobias Banaschewski
, Arun L.W. Bokde
, Yuning Zhang
, Barbara Ruggeri
, Tianye Jia

Marika Kaakinen, Gursharan Kalsi, Pimphen Charoen, Patricia Conrod, Herta Flor, Vincent Frouin, Jürgen Gallinat, Hugh Garavan, Penny A. Gowland, Andreas Heinz, Bernd Ittermann, Christine Macare, Francesca Ducci

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1103-1114
Journal	European Neuropsychopharmacology
Volume	28
Issue number	10
Early online date	11 Aug 2018
DOIs	https://doi.org/10.1016/j.euroneuro.2018.07.101
Publication status	Published - Oct 2018

Bibliographical note

Note: The IMAGEN consortium received support from the following sources: the European Union-funded FP6 Integrated Project IMAGEN (Reinforcementrelated behaviour in normal brain function and psychopathology) (LSHM-CT-2007-037286), the Horizon 2020 funded ERC Advanced Grant 'STRATIFY' (Brain network based stratification of reinforcement-related disorders) (695313), ERANID (Understanding the Interplay between Cultural, Biological and Subjective Factors in Drug Use Pathways) (PR-ST-0416-10004), BRIDGET (JPND: BRain Imaging, cognition Dementia and next generation GEnomics) (MR/N027558/1), the FP7 projects IMAGEMEND(602450; IMAging GEnetics for MENtal Disorders) and MATRICS (603016), the Innovative Medicine Initiative Project EU-AIMS (115300-2), the Medical Research Council Grant 'c-VEDA' (Consortium on Vulnerability to Externalizing Disorders and Addictions) (MR/N000390/1), the Swedish Research Council FORMAS, the Medical Research Council, the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, the Bundesministeriumfür Bildung und Forschung (BMBF grants 01GS08152; 01EV0711; eMED SysAlc01ZX1311A; Forschungsnetz AERIAL 01EE1406A), the Deutsche Forschungsgemeinschaft (DFG grants SM 80/7-1, SM 80/7-2, SFB 940/1). Further support was provided by grants from: ANR (project AF12-NEUR0008-01-WM2NA, and ANR-12-SAMA-0004), the Fondation de France, the Fondation pour la Recherche Médicale, the Mission Interministérielle de Lutte-contre-les-Drogues-et-les-Conduites-Addictives (MILDECA), the Assistance-Publique-Hôpitaux-de-Paris and INSERM (interface grant), Paris Sud University IDEX 2012; the National Institutes of Health, Science Foundation Ireland (16/ERCD/3797), U.S.A. (Axon, Testosterone and Mental Health during Adolescence; RO1 MH085772-01A1), and by NIH Consortium grant U54 EB020403, supported by a cross-NIH alliance that funds Big Data to Knowledge Centres of Excellence.

Keywords

Biological sciences

Access to Document

10.1016/j.euroneuro.2018.07.101

Buxton-J-41863-AAMAccepted author manuscript, 1.86 MBLicence: CC BY-NC-ND

https://doi.org/10.1016/j.euroneuro.2018.07.101

Cite this

Casoni, F., Peters, J., Bromberg, U., Hill, M., Lathrop, M., Martinot, J.-L., Paus, T., Desrivieres, S., Munafo, M., Jarvelin, M.-R., Schumann, G., Buxton, J., Blakemore, A., Veijola, J., Buchel, C., Banaschewski, T., Bokde, A. L. W., Zhang, Y., Ruggeri, B., ... Ducci, F. (2018). A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response. European Neuropsychopharmacology, 28(10), 1103-1114. https://doi.org/10.1016/j.euroneuro.2018.07.101

@article{4e30afcab1124e5c84e7c73f9d91ac6c,

title = "A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response",

keywords = "Biological sciences",

author = "Filippo Casoni and Jan Peters and Uli Bromberg and Matthew Hill and Mark Lathrop and Jean-Luc Martinot and Tomas Paus and Sylvane Desrivieres and Marcus Munafo and Marjo-Riitta Jarvelin and Gunter Schumann and Jessica Buxton and Alexandra Blakemore and Juha Veijola and Christian Buchel and Tobias Banaschewski and Bokde, \{Arun L.W.\} and Yuning Zhang and Barbara Ruggeri and Tianye Jia and Marika Kaakinen and Gursharan Kalsi and Pimphen Charoen and Patricia Conrod and Herta Flor and Vincent Frouin and J{\"u}rgen Gallinat and Hugh Garavan and Gowland, \{Penny A.\} and Andreas Heinz and Bernd Ittermann and Christine Macare and Francesca Ducci",

note = "Note: The IMAGEN consortium received support from the following sources: the European Union-funded FP6 Integrated Project IMAGEN (Reinforcementrelated behaviour in normal brain function and psychopathology) (LSHM-CT-2007-037286), the Horizon 2020 funded ERC Advanced Grant 'STRATIFY' (Brain network based stratification of reinforcement-related disorders) (695313), ERANID (Understanding the Interplay between Cultural, Biological and Subjective Factors in Drug Use Pathways) (PR-ST-0416-10004), BRIDGET (JPND: BRain Imaging, cognition Dementia and next generation GEnomics) (MR/N027558/1), the FP7 projects IMAGEMEND(602450; IMAging GEnetics for MENtal Disorders) and MATRICS (603016), the Innovative Medicine Initiative Project EU-AIMS (115300-2), the Medical Research Council Grant 'c-VEDA' (Consortium on Vulnerability to Externalizing Disorders and Addictions) (MR/N000390/1), the Swedish Research Council FORMAS, the Medical Research Council, the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, the Bundesministeriumf{\"u}r Bildung und Forschung (BMBF grants 01GS08152; 01EV0711; eMED SysAlc01ZX1311A; Forschungsnetz AERIAL 01EE1406A), the Deutsche Forschungsgemeinschaft (DFG grants SM 80/7-1, SM 80/7-2, SFB 940/1). Further support was provided by grants from: ANR (project AF12-NEUR0008-01-WM2NA, and ANR-12-SAMA-0004), the Fondation de France, the Fondation pour la Recherche M{\'e}dicale, the Mission Interminist{\'e}rielle de Lutte-contre-les-Drogues-et-les-Conduites-Addictives (MILDECA), the Assistance-Publique-H{\^o}pitaux-de-Paris and INSERM (interface grant), Paris Sud University IDEX 2012; the National Institutes of Health, Science Foundation Ireland (16/ERCD/3797), U.S.A. (Axon, Testosterone and Mental Health during Adolescence; RO1 MH085772-01A1), and by NIH Consortium grant U54 EB020403, supported by a cross-NIH alliance that funds Big Data to Knowledge Centres of Excellence.",

year = "2018",

month = oct,

doi = "10.1016/j.euroneuro.2018.07.101",

language = "English",

volume = "28",

pages = "1103--1114",

journal = "European Neuropsychopharmacology",

issn = "0924-977X",

publisher = "Elsevier B.V.",

number = "10",

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Casoni, F, Peters, J, Bromberg, U, Hill, M, Lathrop, M, Martinot, J-L, Paus, T, Desrivieres, S, Munafo, M, Jarvelin, M-R, Schumann, G, Buxton, J, Blakemore, A, Veijola, J, Buchel, C, Banaschewski, T, Bokde, ALW, Zhang, Y, Ruggeri, B, Jia, T, Kaakinen, M, Kalsi, G, Charoen, P, Conrod, P, Flor, H, Frouin, V, Gallinat, J, Garavan, H, Gowland, PA, Heinz, A, Ittermann, B, Macare, C & Ducci, F 2018, 'A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response', European Neuropsychopharmacology, vol. 28, no. 10, pp. 1103-1114. https://doi.org/10.1016/j.euroneuro.2018.07.101

TY - JOUR

T1 - A neurobiological pathway to smoking in adolescence

T2 - TTC12-ANKK1-DRD2 variants and reward response

AU - Casoni, Filippo

AU - Peters, Jan

AU - Bromberg, Uli

AU - Hill, Matthew

AU - Lathrop, Mark

AU - Martinot, Jean-Luc

AU - Paus, Tomas

AU - Desrivieres, Sylvane

AU - Munafo, Marcus

AU - Jarvelin, Marjo-Riitta

AU - Schumann, Gunter

AU - Buxton, Jessica

AU - Blakemore, Alexandra

AU - Veijola, Juha

AU - Buchel, Christian

AU - Banaschewski, Tobias

AU - Bokde, Arun L.W.

AU - Zhang, Yuning

AU - Ruggeri, Barbara

AU - Jia, Tianye

AU - Kaakinen, Marika

AU - Kalsi, Gursharan

AU - Charoen, Pimphen

AU - Conrod, Patricia

AU - Flor, Herta

AU - Frouin, Vincent

AU - Gallinat, Jürgen

AU - Garavan, Hugh

AU - Gowland, Penny A.

AU - Heinz, Andreas

AU - Ittermann, Bernd

AU - Macare, Christine

AU - Ducci, Francesca

N1 - Note: The IMAGEN consortium received support from the following sources: the European Union-funded FP6 Integrated Project IMAGEN (Reinforcementrelated behaviour in normal brain function and psychopathology) (LSHM-CT-2007-037286), the Horizon 2020 funded ERC Advanced Grant 'STRATIFY' (Brain network based stratification of reinforcement-related disorders) (695313), ERANID (Understanding the Interplay between Cultural, Biological and Subjective Factors in Drug Use Pathways) (PR-ST-0416-10004), BRIDGET (JPND: BRain Imaging, cognition Dementia and next generation GEnomics) (MR/N027558/1), the FP7 projects IMAGEMEND(602450; IMAging GEnetics for MENtal Disorders) and MATRICS (603016), the Innovative Medicine Initiative Project EU-AIMS (115300-2), the Medical Research Council Grant 'c-VEDA' (Consortium on Vulnerability to Externalizing Disorders and Addictions) (MR/N000390/1), the Swedish Research Council FORMAS, the Medical Research Council, the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, the Bundesministeriumfür Bildung und Forschung (BMBF grants 01GS08152; 01EV0711; eMED SysAlc01ZX1311A; Forschungsnetz AERIAL 01EE1406A), the Deutsche Forschungsgemeinschaft (DFG grants SM 80/7-1, SM 80/7-2, SFB 940/1). Further support was provided by grants from: ANR (project AF12-NEUR0008-01-WM2NA, and ANR-12-SAMA-0004), the Fondation de France, the Fondation pour la Recherche Médicale, the Mission Interministérielle de Lutte-contre-les-Drogues-et-les-Conduites-Addictives (MILDECA), the Assistance-Publique-Hôpitaux-de-Paris and INSERM (interface grant), Paris Sud University IDEX 2012; the National Institutes of Health, Science Foundation Ireland (16/ERCD/3797), U.S.A. (Axon, Testosterone and Mental Health during Adolescence; RO1 MH085772-01A1), and by NIH Consortium grant U54 EB020403, supported by a cross-NIH alliance that funds Big Data to Knowledge Centres of Excellence.

PY - 2018/10

Y1 - 2018/10

KW - Biological sciences

U2 - 10.1016/j.euroneuro.2018.07.101

DO - 10.1016/j.euroneuro.2018.07.101

M3 - Article

SN - 0924-977X

VL - 28

SP - 1103

EP - 1114

JO - European Neuropsychopharmacology

JF - European Neuropsychopharmacology

IS - 10

ER -