A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation

Catherine F. Oliver; Sandeep Modi; Michael J. Sutcliffe; William U. Primrose; Lu-Yun Lian; Gordon C.K. Roberts

doi:10.1021/bi962826c

A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation

Catherine F. Oliver, Sandeep Modi, Michael J. Sutcliffe, William U. Primrose, Lu-Yun Lian, Gordon C.K. Roberts

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1567-1572
Journal	Biochemistry
Volume	36
Issue number	7
DOIs	https://doi.org/10.1021/bi962826c
Publication status	Published - 18 Feb 1997
Externally published	Yes

Keywords

Chemistry

Access to Document

10.1021/bi962826c

http://dx.doi.org/10.1021/bi962826c

Cite this

@article{03ea73ccdd3f4dbf9fb989a195768074,

title = "A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation",

keywords = "Chemistry",

author = "Oliver, \{Catherine F.\} and Sandeep Modi and Sutcliffe, \{Michael J.\} and Primrose, \{William U.\} and Lu-Yun Lian and Roberts, \{Gordon C.K.\}",

year = "1997",

month = feb,

day = "18",

doi = "10.1021/bi962826c",

language = "English",

volume = "36",

pages = "1567--1572",

journal = "Biochemistry",

issn = "0006-2960",

publisher = "American Chemical Society",

number = "7",

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T1 - A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation

AU - Oliver, Catherine F.

AU - Modi, Sandeep

AU - Sutcliffe, Michael J.

AU - Primrose, William U.

AU - Lian, Lu-Yun

AU - Roberts, Gordon C.K.

PY - 1997/2/18

Y1 - 1997/2/18

KW - Chemistry

U2 - 10.1021/bi962826c

DO - 10.1021/bi962826c

M3 - Article

SN - 0006-2960

VL - 36

SP - 1567

EP - 1572

JO - Biochemistry

JF - Biochemistry

IS - 7

ER -