Aryloxy diester phosphonamidate prodrugs of phosphoantigens (ProPAgens) as potent activators of V╬│9/V╬┤2 T-cell immune responses

Hachemi Kadri; Taher E. Taher; Qin Xu; Maria Sharif; Elizabeth Ashby; Richard T. Bryan; Benjamin E. Willcox; Youcef Mehellou

doi:10.1021/acs.jmedchem.0c01232

Aryloxy diester phosphonamidate prodrugs of phosphoantigens (ProPAgens) as potent activators of V╬│9/V╬┤2 T-cell immune responses

Hachemi Kadri
, Taher E. Taher
, Qin Xu
, Maria Sharif
, Elizabeth Ashby
, Richard T. Bryan
, Benjamin E. Willcox
, Youcef Mehellou

Cardiff University
University of Birmingham

Research output: Contribution to journal › Article › peer-review

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Original language	English
Pages (from-to)	11258-11270
Journal	Journal of Medicinal Chemistry
Volume	63
Issue number	19
Early online date	15 Sept 2020
DOIs	https://doi.org/10.1021/acs.jmedchem.0c01232
Publication status	Published - 8 Oct 2020

Bibliographical note

Note: The work was supported by Wellcome Trust [grant codes: 514079, 099266/Z/12/Z and 200983/Z/16/Z].

Keywords

Chemistry

Access to Document

10.1021/acs.jmedchem.0c01232

Kadri-H-51429-VoRFinal published version, 2.01 MBLicence: CC BY

https://doi.org/10.1021/acs.jmedchem.0c01232

Cite this

@article{05340244dc3f4056bffb28b053f13d7a,

title = "Aryloxy diester phosphonamidate prodrugs of phosphoantigens (ProPAgens) as potent activators of V╬│9/V╬┤2 T-cell immune responses",

keywords = "Chemistry",

author = "Hachemi Kadri and Taher, \{Taher E.\} and Qin Xu and Maria Sharif and Elizabeth Ashby and Bryan, \{Richard T.\} and Willcox, \{Benjamin E.\} and Youcef Mehellou",

note = "Note: The work was supported by Wellcome Trust [grant codes: 514079, 099266/Z/12/Z and 200983/Z/16/Z].",

year = "2020",

month = oct,

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doi = "10.1021/acs.jmedchem.0c01232",

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journal = "Journal of Medicinal Chemistry",

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T1 - Aryloxy diester phosphonamidate prodrugs of phosphoantigens (ProPAgens) as potent activators of V╬│9/V╬┤2 T-cell immune responses

AU - Kadri, Hachemi

AU - Taher, Taher E.

AU - Xu, Qin

AU - Sharif, Maria

AU - Ashby, Elizabeth

AU - Bryan, Richard T.

AU - Willcox, Benjamin E.

AU - Mehellou, Youcef

N1 - Note: The work was supported by Wellcome Trust [grant codes: 514079, 099266/Z/12/Z and 200983/Z/16/Z].

PY - 2020/10/8

Y1 - 2020/10/8

KW - Chemistry

U2 - 10.1021/acs.jmedchem.0c01232

DO - 10.1021/acs.jmedchem.0c01232

M3 - Article

SN - 0022-2623

VL - 63

SP - 11258

EP - 11270

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 19

ER -