Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation

Sam Hay; Christopher Pudney; Parvinder Hothi; Linus, O. Johannissen; Laura Masgrau; Jiayun Pang; David Leys; Michael, J. Sutcliffe; Nigel, S. Scrutton

doi:10.1042/BST0360016

Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation

Sam Hay
, Christopher Pudney
, Parvinder Hothi
, Linus, O. Johannissen
, Laura Masgrau
, Jiayun Pang
, David Leys
, Michael, J. Sutcliffe
, Nigel, S. Scrutton

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	16-21
Journal	Biochemical Society Transactions
Volume	36
Issue number	1
DOIs	https://doi.org/10.1042/BST0360016
Publication status	Published - 1 Feb 2008
Externally published	Yes

Keywords

Chemistry

Access to Document

10.1042/BST0360016

http://dx.doi.org/10.1042/BST0360016

Cite this

Hay, S., Pudney, C., Hothi, P., Johannissen, L. O., Masgrau, L., Pang, J., Leys, D., Sutcliffe, M. J., & Scrutton, N. S. (2008). Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation. Biochemical Society Transactions, 36(1), 16-21. https://doi.org/10.1042/BST0360016

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keywords = "Chemistry",

author = "Sam Hay and Christopher Pudney and Parvinder Hothi and Johannissen, \{Linus, O.\} and Laura Masgrau and Jiayun Pang and David Leys and Sutcliffe, \{Michael, J.\} and Scrutton, \{Nigel, S.\}",

year = "2008",

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Hay, S, Pudney, C, Hothi, P, Johannissen, LO, Masgrau, L, Pang, J, Leys, D, Sutcliffe, MJ & Scrutton, NS 2008, 'Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation', Biochemical Society Transactions, vol. 36, no. 1, pp. 16-21. https://doi.org/10.1042/BST0360016

Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation. / Hay, Sam; Pudney, Christopher; Hothi, Parvinder et al.
In: Biochemical Society Transactions, Vol. 36, No. 1, 01.02.2008, p. 16-21.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation

AU - Hay, Sam

AU - Pudney, Christopher

AU - Hothi, Parvinder

AU - Johannissen, Linus, O.

AU - Masgrau, Laura

AU - Pang, Jiayun

AU - Leys, David

AU - Sutcliffe, Michael, J.

AU - Scrutton, Nigel, S.

PY - 2008/2/1

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KW - Chemistry

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M3 - Article

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SP - 16

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JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

IS - 1

ER -