CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G0/G1 inhibiting pRB phosphorylation

Sachin Mahale; Carine Aubry; A. James Wilson; Paul, R. Jenkins; Jean-Didier Mar├®chal; Michael, J. Sutcliffe; Bhabatosh Chaudhuri

doi:10.1016/j.bmcl.2006.05.065

CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G0/G1 inhibiting pRB phosphorylation

Sachin Mahale
, Carine Aubry
, A. James Wilson
, Paul, R. Jenkins
, Jean-Didier Mar├®chal
, Michael, J. Sutcliffe
, Bhabatosh Chaudhuri

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	4272-4278
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	16
Issue number	16
DOIs	https://doi.org/10.1016/j.bmcl.2006.05.065
Publication status	Published - Aug 2006
Externally published	Yes

Keywords

Chemistry

Access to Document

10.1016/j.bmcl.2006.05.065

http://dx.doi.org/doi:10.1016/j.bmcl.2006.05.065

Cite this

@article{00cc9b6c2e204197b24811756facc70a,

title = "CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G0/G1 inhibiting pRB phosphorylation",

keywords = "Chemistry",

author = "Sachin Mahale and Carine Aubry and Wilson, \{A. James\} and Jenkins, \{Paul, R.\} and Jean-Didier Mar├{\textregistered}chal and Sutcliffe, \{Michael, J.\} and Bhabatosh Chaudhuri",

year = "2006",

month = aug,

doi = "10.1016/j.bmcl.2006.05.065",

language = "English",

volume = "16",

pages = "4272--4278",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Ltd",

number = "16",

}

TY - JOUR

T1 - CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G0/G1 inhibiting pRB phosphorylation

AU - Mahale, Sachin

AU - Aubry, Carine

AU - Wilson, A. James

AU - Jenkins, Paul, R.

AU - Mar├®chal, Jean-Didier

AU - Sutcliffe, Michael, J.

AU - Chaudhuri, Bhabatosh

PY - 2006/8

Y1 - 2006/8

KW - Chemistry

U2 - 10.1016/j.bmcl.2006.05.065

DO - 10.1016/j.bmcl.2006.05.065

M3 - Article

SN - 0960-894X

VL - 16

SP - 4272

EP - 4278

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 16

ER -