Design, synthesis and evaluation of novel 2-substituted 3-hydroxypyridin-4-ones: structure activity investigation of metalloenzyme inhibition by iron chelators

Zu D. Liu; Reem Kayyali; Robert C. Hider; John B. Porter; Anthony E. Theobald

doi:10.1021/jm010817i

Design, synthesis and evaluation of novel 2-substituted 3-hydroxypyridin-4-ones: structure activity investigation of metalloenzyme inhibition by iron chelators

Zu D. Liu
, Reem Kayyali
, Robert C. Hider
, John B. Porter
, Anthony E. Theobald

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	631-639
Journal	Journal of Medicinal Chemistry
Volume	45
Issue number	3
DOIs	https://doi.org/10.1021/jm010817i
Publication status	Published - Jan 2002

Keywords

Allied health professions and studies

Access to Document

10.1021/jm010817i

http://dx.doi.org/10.1021/jm010817i

Cite this

@article{6a58092fe31a40cbb31a8f450f33c22c,

title = "Design, synthesis and evaluation of novel 2-substituted 3-hydroxypyridin-4-ones: structure activity investigation of metalloenzyme inhibition by iron chelators",

keywords = "Allied health professions and studies",

author = "Liu, \{Zu D.\} and Reem Kayyali and Hider, \{Robert C.\} and Porter, \{John B.\} and Theobald, \{Anthony E.\}",

year = "2002",

month = jan,

doi = "10.1021/jm010817i",

language = "English",

volume = "45",

pages = "631--639",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

number = "3",

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TY - JOUR

T1 - Design, synthesis and evaluation of novel 2-substituted 3-hydroxypyridin-4-ones

T2 - structure activity investigation of metalloenzyme inhibition by iron chelators

AU - Liu, Zu D.

AU - Kayyali, Reem

AU - Hider, Robert C.

AU - Porter, John B.

AU - Theobald, Anthony E.

PY - 2002/1

Y1 - 2002/1

KW - Allied health professions and studies

U2 - 10.1021/jm010817i

DO - 10.1021/jm010817i

M3 - Article

SN - 0022-2623

VL - 45

SP - 631

EP - 639

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 3

ER -