Detection of (NAD(P)H: Quinone oxidoreductase-1, EC 1.6.99.2) 609C -> T and 465C -> T polymorphisms in formalin-fixed, paraffin-embedded human tumour tissue using PCR-RFLP

Roger M. Phillips, Saurajyoti Basu, John E. Brown, G. Michael Flannigan, Paul M. Loadman, Sandie W. Martin, Brian Naylor, Rajiv Puri, Tariq Shah

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1005-1010
JournalInternational Journal of Oncology
Volume24
Issue number4
Publication statusPublished - Apr 2004
Externally publishedYes

Keywords

  • nqo1
  • 465c -> t polymorphisms
  • single nucleotide polymorphism
  • dt-diaphorase
  • quinone-oxidoreductase
  • mitomycin-c
  • dna extraction
  • nad(p)h
  • gene
  • bioactivation
  • chemotherapy
  • Chemistry

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