Abstract
Microarrays are now established technologies which are considered as key to gene expression analysis. Their study is usually achieved by using clustering techniques. Genomic signal processing is a new area of research that combines genomics with digital signal processing methodologies. In this paper, we present a comparative analysis of two genomic signal processing methods for robust microarray data clustering. Techniques based on Fractal Dimension and Discrete Wavelet Decomposition with Vector Quantization are validated for standard data sets. Comparative analysis of the results indicates that these methods provide improved clustering accuracy compared to some conventional clustering techniques. Moreover, these classifiers don't require any prior training procedures.
| Original language | English |
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| DOIs | |
| Publication status | Published - 23 Aug 2008 |
| Event | 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Vancouver, Canada Duration: 20 Aug 2008 → 25 Aug 2008 |
Conference
| Conference | 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society |
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| Period | 20/08/08 → 25/08/08 |
Keywords
- gene-expression data
- component analysis
- tumor classification
- Computer science and informatics