Glowing jellyfish, luminescence and a molecule called coelentrazine

Keith Jones; Frank Hibbert; Martine Keenan

doi:10.1016/S0167-7799(99)01379-7

Glowing jellyfish, luminescence and a molecule called coelentrazine

Keith Jones
, Frank Hibbert
, Martine Keenan

Research output: Contribution to journal › Article › peer-review

Abstract

Luminescence has assumed an important role in analytical biochemistry and molecular biology as an extremely sensitive method for determining the concentration of specific ions and molecules. The luminescent system of the jellyfish Aequorea victoria consists of the photoprotein aequorin, which contains the molecule coelenterazine as a prosthetic group and shows considerable potential in this area.

Original language	English
Pages (from-to)	477-481
Journal	Trends in Biotechnology
Volume	17
Issue number	12
DOIs	https://doi.org/10.1016/S0167-7799(99)01379-7
Publication status	Published - 1 Dec 1999
Externally published	Yes

Bibliographical note

Note: This work was supported by the Biotechnology and Biological Sciences Research Council.

Keywords

superoxide
photoprotein aequorin
chemiluminescent probe
endoplasmic-reticulum
recombinant aequorin
superoxide anion
functional part
calcium
bioluminescence
analogs
mechanism
Chemistry

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10.1016/S0167-7799(99)01379-7

http://dx.doi.org/10.1016/S0167-7799(99)01379-7

Cite this

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title = "Glowing jellyfish, luminescence and a molecule called coelentrazine",

abstract = "Luminescence has assumed an important role in analytical biochemistry and molecular biology as an extremely sensitive method for determining the concentration of specific ions and molecules. The luminescent system of the jellyfish Aequorea victoria consists of the photoprotein aequorin, which contains the molecule coelenterazine as a prosthetic group and shows considerable potential in this area.",

keywords = "superoxide, photoprotein aequorin, chemiluminescent probe, endoplasmic-reticulum, recombinant aequorin, superoxide anion, functional part, calcium, bioluminescence, analogs, mechanism, Chemistry",

author = "Keith Jones and Frank Hibbert and Martine Keenan",

note = "Note: This work was supported by the Biotechnology and Biological Sciences Research Council.",

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doi = "10.1016/S0167-7799(99)01379-7",

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T1 - Glowing jellyfish, luminescence and a molecule called coelentrazine

AU - Jones, Keith

AU - Hibbert, Frank

AU - Keenan, Martine

N1 - Note: This work was supported by the Biotechnology and Biological Sciences Research Council.

PY - 1999/12/1

Y1 - 1999/12/1

N2 - Luminescence has assumed an important role in analytical biochemistry and molecular biology as an extremely sensitive method for determining the concentration of specific ions and molecules. The luminescent system of the jellyfish Aequorea victoria consists of the photoprotein aequorin, which contains the molecule coelenterazine as a prosthetic group and shows considerable potential in this area.

AB - Luminescence has assumed an important role in analytical biochemistry and molecular biology as an extremely sensitive method for determining the concentration of specific ions and molecules. The luminescent system of the jellyfish Aequorea victoria consists of the photoprotein aequorin, which contains the molecule coelenterazine as a prosthetic group and shows considerable potential in this area.

KW - superoxide

KW - photoprotein aequorin

KW - chemiluminescent probe

KW - endoplasmic-reticulum

KW - recombinant aequorin

KW - superoxide anion

KW - functional part

KW - calcium

KW - bioluminescence

KW - analogs

KW - mechanism

KW - Chemistry

UR - http://www.ncbi.nlm.nih.gov/pubmed/10557160

U2 - 10.1016/S0167-7799(99)01379-7

DO - 10.1016/S0167-7799(99)01379-7

M3 - Article

C2 - 10557160

SN - 0167-7799

VL - 17

SP - 477

EP - 481

JO - Trends in Biotechnology

JF - Trends in Biotechnology

IS - 12

ER -

Glowing jellyfish, luminescence and a molecule called coelentrazine

Abstract

Bibliographical note

Keywords

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