Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach

Ali Ryan; Elena Polycarpou; Nathan A. Lack; Dimitrios Evangelopoulos; Christian Sieg; Alice Halman; Sanjib Bhakta; Olga Eleftheriadou; Timothy D. McHugh; Sebastian Keany; Edward D. Lowe; Romain Ballet; Areej Abuhammad; William R. Jacobs; Alessio Ciulli; Edith Sim

doi:10.1111/bph.13810

Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach

Ali Ryan
, Elena Polycarpou
, Nathan A. Lack
, Dimitrios Evangelopoulos
, Christian Sieg
, Alice Halman
, Sanjib Bhakta
, Olga Eleftheriadou
, Timothy D. McHugh
, Sebastian Keany
, Edward D. Lowe
, Romain Ballet
, Areej Abuhammad
, William R. Jacobs
, Alessio Ciulli
, Edith Sim

Research output: Contribution to journal › Article › peer-review

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Original language	English
Pages (from-to)	2209-2224
Journal	British Journal of Pharmacology
Volume	174
Issue number	14
Early online date	9 May 2017
DOIs	https://doi.org/10.1111/bph.13810
Publication status	Published - 31 Jul 2017

Keywords

Pharmacy

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10.1111/bph.13810

Ryan-A-37911-AAMAccepted author manuscript, 1.81 MBLicence: Unspecified

https://dx.doi.org/10.1111/bph.13810

Cite this

Ryan, A., Polycarpou, E., Lack, N. A., Evangelopoulos, D., Sieg, C., Halman, A., Bhakta, S., Eleftheriadou, O., McHugh, T. D., Keany, S., Lowe, E. D., Ballet, R., Abuhammad, A., Jacobs, W. R., Ciulli, A., & Sim, E. (2017). Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach. British Journal of Pharmacology, 174(14), 2209-2224. https://doi.org/10.1111/bph.13810

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author = "Ali Ryan and Elena Polycarpou and Lack, \{Nathan A.\} and Dimitrios Evangelopoulos and Christian Sieg and Alice Halman and Sanjib Bhakta and Olga Eleftheriadou and McHugh, \{Timothy D.\} and Sebastian Keany and Lowe, \{Edward D.\} and Romain Ballet and Areej Abuhammad and Jacobs, \{William R.\} and Alessio Ciulli and Edith Sim",

year = "2017",

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day = "31",

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Ryan, A, Polycarpou, E, Lack, NA, Evangelopoulos, D, Sieg, C, Halman, A, Bhakta, S, Eleftheriadou, O, McHugh, TD, Keany, S, Lowe, ED, Ballet, R, Abuhammad, A, Jacobs, WR, Ciulli, A & Sim, E 2017, 'Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach', British Journal of Pharmacology, vol. 174, no. 14, pp. 2209-2224. https://doi.org/10.1111/bph.13810

TY - JOUR

T1 - Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach

AU - Ryan, Ali

AU - Polycarpou, Elena

AU - Lack, Nathan A.

AU - Evangelopoulos, Dimitrios

AU - Sieg, Christian

AU - Halman, Alice

AU - Bhakta, Sanjib

AU - Eleftheriadou, Olga

AU - McHugh, Timothy D.

AU - Keany, Sebastian

AU - Lowe, Edward D.

AU - Ballet, Romain

AU - Abuhammad, Areej

AU - Jacobs, William R.

AU - Ciulli, Alessio

AU - Sim, Edith

PY - 2017/7/31

Y1 - 2017/7/31

KW - Pharmacy

U2 - 10.1111/bph.13810

DO - 10.1111/bph.13810

M3 - Article

SN - 0007-1188

VL - 174

SP - 2209

EP - 2224

JO - British Journal of Pharmacology

JF - British Journal of Pharmacology

IS - 14

ER -