Kinetin riboside and its ProTides activate the Parkinson's disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization

Laura Osgerby; Yu Chiang Lai; Peter J. Thornton; Joseph Amalfitano; Cécile S. Le Duff; Iqra Jabeen; Hachemi Kadri; Ageo Miccoli; James H.R. Tucker; Miratul M.K. Muqit; Youcef Mehellou

doi:10.1021/acs.jmedchem.6b01897

Kinetin riboside and its ProTides activate the Parkinson's disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization

Laura Osgerby
, Yu Chiang Lai
, Peter J. Thornton
, Joseph Amalfitano
, Cécile S. Le Duff
, Iqra Jabeen
, Hachemi Kadri
, Ageo Miccoli
, James H.R. Tucker
, Miratul M.K. Muqit
, Youcef Mehellou

Research output: Contribution to journal › Article › peer-review

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Original language	English
Pages (from-to)	3518-3524
Journal	Journal of Medicinal Chemistry
Volume	60
Issue number	8
Early online date	17 Mar 2017
DOIs	https://doi.org/10.1021/acs.jmedchem.6b01897
Publication status	Published - 27 Apr 2017

Keywords

Biological sciences

Access to Document

10.1021/acs.jmedchem.6b01897

Kadri-H-51474-VoRFinal published version, 1.88 MBLicence: CC BY

https://doi.org/10.1021/acs.jmedchem.6b01897

Cite this

Osgerby, L., Lai, Y. C., Thornton, P. J., Amalfitano, J., Le Duff, C. S., Jabeen, I., Kadri, H., Miccoli, A., Tucker, J. H. R., Muqit, M. M. K., & Mehellou, Y. (2017). Kinetin riboside and its ProTides activate the Parkinson's disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization. Journal of Medicinal Chemistry, 60(8), 3518-3524. https://doi.org/10.1021/acs.jmedchem.6b01897

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title = "Kinetin riboside and its ProTides activate the Parkinson's disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization",

keywords = "Biological sciences",

author = "Laura Osgerby and Lai, \{Yu Chiang\} and Thornton, \{Peter J.\} and Joseph Amalfitano and \{Le Duff\}, \{C{\'e}cile S.\} and Iqra Jabeen and Hachemi Kadri and Ageo Miccoli and Tucker, \{James H.R.\} and Muqit, \{Miratul M.K.\} and Youcef Mehellou",

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day = "27",

doi = "10.1021/acs.jmedchem.6b01897",

language = "English",

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Osgerby, L, Lai, YC, Thornton, PJ, Amalfitano, J, Le Duff, CS, Jabeen, I, Kadri, H, Miccoli, A, Tucker, JHR, Muqit, MMK & Mehellou, Y 2017, 'Kinetin riboside and its ProTides activate the Parkinson's disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization', Journal of Medicinal Chemistry, vol. 60, no. 8, pp. 3518-3524. https://doi.org/10.1021/acs.jmedchem.6b01897

TY - JOUR

T1 - Kinetin riboside and its ProTides activate the Parkinson's disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization

AU - Osgerby, Laura

AU - Lai, Yu Chiang

AU - Thornton, Peter J.

AU - Amalfitano, Joseph

AU - Le Duff, Cécile S.

AU - Jabeen, Iqra

AU - Kadri, Hachemi

AU - Miccoli, Ageo

AU - Tucker, James H.R.

AU - Muqit, Miratul M.K.

AU - Mehellou, Youcef

PY - 2017/4/27

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KW - Biological sciences

U2 - 10.1021/acs.jmedchem.6b01897

DO - 10.1021/acs.jmedchem.6b01897

M3 - Article

SN - 0022-2623

VL - 60

SP - 3518

EP - 3524

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 8

ER -