' Lactobacillus fermentum ' 3872 genome sequencing reveals plasmid and chromosomal genes potentially involved in a probiotic activity.

Burhan Lehri; Alan Seddon; Andrey Karlyshev

doi:10.1093/femsle/fnv068

' Lactobacillus fermentum ' 3872 genome sequencing reveals plasmid and chromosomal genes potentially involved in a probiotic activity.

Burhan Lehri
, Alan Seddon
, Andrey Karlyshev

Research output: Contribution to journal › Article › peer-review

Abstract

In this report we describe a ' Lactobacillus fermentum ' 3872 plasmid (pLF3872) not previously found in any other strain of this species. The analysis of the complete sequence of this plasmid revealed the presence of a gene encoding a large collagen binding protein (CBP), as well as the genes responsible for plasmid maintenance and conjugation. Potential roles of CBP and a chromosomally encoded fibronectin-binding protein (FbpA) in probiotic activity are discussed.

Original language	English
Journal	FEMS Microbiology Letters
Volume	362
Issue number	11
DOIs	https://doi.org/10.1093/femsle/fnv068
Publication status	Published - 1 Jun 2015

Bibliographical note

Note: This is a pre-copyedited, author-produced PDF of an article accepted for publication in FEMS microbiology letters following peer review. The version of record ' Lactobacillus fermentum ' 3872 genome sequencing reveals plasmid and chromosomal genes potentially involved in a probiotic activity. FEMS microbiology letters, 362(11), is available online at: http://dx.doi.org/10.1093/femsle/fnv068.

Keywords

Biological sciences
Lactobacillus fermentum
adhesion
collagen binding protein
conjugative plasmid
host cell receptors
peptidoglycan hydrolase
probiotics

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10.1093/femsle/fnv068

Karlyshev-31503Accepted author manuscript, 162 KBLicence: Unspecified

http://dx.doi.org/10.1093/femsle/fnv068

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title = "' Lactobacillus fermentum ' 3872 genome sequencing reveals plasmid and chromosomal genes potentially involved in a probiotic activity.",

abstract = "In this report we describe a ' Lactobacillus fermentum ' 3872 plasmid (pLF3872) not previously found in any other strain of this species. The analysis of the complete sequence of this plasmid revealed the presence of a gene encoding a large collagen binding protein (CBP), as well as the genes responsible for plasmid maintenance and conjugation. Potential roles of CBP and a chromosomally encoded fibronectin-binding protein (FbpA) in probiotic activity are discussed.",

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author = "Burhan Lehri and Alan Seddon and Andrey Karlyshev",

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doi = "10.1093/femsle/fnv068",

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AU - Seddon, Alan

AU - Karlyshev, Andrey

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AB - In this report we describe a ' Lactobacillus fermentum ' 3872 plasmid (pLF3872) not previously found in any other strain of this species. The analysis of the complete sequence of this plasmid revealed the presence of a gene encoding a large collagen binding protein (CBP), as well as the genes responsible for plasmid maintenance and conjugation. Potential roles of CBP and a chromosomally encoded fibronectin-binding protein (FbpA) in probiotic activity are discussed.

KW - Biological sciences

KW - Lactobacillus fermentum

KW - adhesion

KW - collagen binding protein

KW - conjugative plasmid

KW - host cell receptors

KW - peptidoglycan hydrolase

KW - probiotics

UR - http://www.ncbi.nlm.nih.gov/pubmed/25908870

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DO - 10.1093/femsle/fnv068

M3 - Article

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SN - 0378-1097

VL - 362

JO - FEMS Microbiology Letters

JF - FEMS Microbiology Letters

IS - 11

ER -

' Lactobacillus fermentum ' 3872 genome sequencing reveals plasmid and chromosomal genes potentially involved in a probiotic activity.

Abstract

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Keywords

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