Mapping of the diabetes polygene Idd3 on mouse Chromosome 3 using novel congenic strains

C. J. Lord; S. K. Bohlander; E. A. Hopes; C. T. Montague; N. J. Hill; J.-B. Prins; L. B. Peterson; L. S. Wicker; J. A. Todd; P. Denny

doi:10.1007/BF00352359

Mapping of the diabetes polygene Idd3 on mouse Chromosome 3 using novel congenic strains

C. J. Lord
, S. K. Bohlander
, E. A. Hopes
, C. T. Montague
, N. J. Hill
, J.-B. Prins
, L. B. Peterson
, L. S. Wicker
, J. A. Todd
, P. Denny

Research output: Contribution to journal › Article › peer-review

Abstract

Development of novel congenic mouse strains has allowed us to better define the location of the diabetogenic locus, Idd3, on Chromosome (Chr) 3. Congenic strains were identified by use of published and newly developed microsatellite markers, their genomes fingerprinted by a rapid, fluorescence-based approach, and their susceptibility to type 1 diabetes evaluated. The maximum interval containing Idd3 is now approximately 4 cM.

Original language	English
Pages (from-to)	563-570
Journal	Mammalian Genome
Volume	6
Issue number	9
DOIs	https://doi.org/10.1007/BF00352359
Publication status	Published - 30 Sept 1995
Externally published	Yes

Keywords

Allied health professions and studies

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10.1007/BF00352359

https://doi.org/10.1007/BF00352359

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title = "Mapping of the diabetes polygene Idd3 on mouse Chromosome 3 using novel congenic strains",

abstract = "Development of novel congenic mouse strains has allowed us to better define the location of the diabetogenic locus, Idd3, on Chromosome (Chr) 3. Congenic strains were identified by use of published and newly developed microsatellite markers, their genomes fingerprinted by a rapid, fluorescence-based approach, and their susceptibility to type 1 diabetes evaluated. The maximum interval containing Idd3 is now approximately 4 cM.",

keywords = "Allied health professions and studies",

author = "Lord, \{C. J.\} and Bohlander, \{S. K.\} and Hopes, \{E. A.\} and Montague, \{C. T.\} and Hill, \{N. J.\} and J.-B. Prins and Peterson, \{L. B.\} and Wicker, \{L. S.\} and Todd, \{J. A.\} and P. Denny",

year = "1995",

month = sep,

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doi = "10.1007/BF00352359",

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TY - JOUR

T1 - Mapping of the diabetes polygene Idd3 on mouse Chromosome 3 using novel congenic strains

AU - Lord, C. J.

AU - Bohlander, S. K.

AU - Hopes, E. A.

AU - Montague, C. T.

AU - Hill, N. J.

AU - Prins, J.-B.

AU - Peterson, L. B.

AU - Wicker, L. S.

AU - Todd, J. A.

AU - Denny, P.

PY - 1995/9/30

Y1 - 1995/9/30

N2 - Development of novel congenic mouse strains has allowed us to better define the location of the diabetogenic locus, Idd3, on Chromosome (Chr) 3. Congenic strains were identified by use of published and newly developed microsatellite markers, their genomes fingerprinted by a rapid, fluorescence-based approach, and their susceptibility to type 1 diabetes evaluated. The maximum interval containing Idd3 is now approximately 4 cM.

AB - Development of novel congenic mouse strains has allowed us to better define the location of the diabetogenic locus, Idd3, on Chromosome (Chr) 3. Congenic strains were identified by use of published and newly developed microsatellite markers, their genomes fingerprinted by a rapid, fluorescence-based approach, and their susceptibility to type 1 diabetes evaluated. The maximum interval containing Idd3 is now approximately 4 cM.

KW - Allied health professions and studies

UR - https://www.ncbi.nlm.nih.gov/pubmed/8535060

U2 - 10.1007/BF00352359

DO - 10.1007/BF00352359

M3 - Article

C2 - 8535060

SN - 0938-8990

VL - 6

SP - 563

EP - 570

JO - Mammalian Genome

JF - Mammalian Genome

IS - 9

ER -

Mapping of the diabetes polygene Idd3 on mouse Chromosome 3 using novel congenic strains

Abstract

Keywords

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