Multiple substrate binding by cytochrome P450 3A4: Estimation of the number of bound substrate molecules

Yury Kapelyukh; Mark, J.I. Paine; Jean-Didier Mar├®chal; Michael, J. Sutcliffe; C. Roland Wolf; Gordon, C.K. Roberts

doi:10.1124/dmd.108.021733

Multiple substrate binding by cytochrome P450 3A4: Estimation of the number of bound substrate molecules

Yury Kapelyukh
, Mark, J.I. Paine
, Jean-Didier Mar├®chal
, Michael, J. Sutcliffe
, C. Roland Wolf
, Gordon, C.K. Roberts

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	2136-2144
Journal	Drug Metabolism and Disposition
Volume	36
Issue number	10
DOIs	https://doi.org/10.1124/dmd.108.021733
Publication status	Published - Oct 2008

Keywords

Chemistry

Access to Document

10.1124/dmd.108.021733

http://dx.doi.org/10.1124/dmd.108.021733

Cite this

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title = "Multiple substrate binding by cytochrome P450 3A4: Estimation of the number of bound substrate molecules",

keywords = "Chemistry",

author = "Yury Kapelyukh and Paine, \{Mark, J.I.\} and Jean-Didier Mar├{\textregistered}chal and Sutcliffe, \{Michael, J.\} and Wolf, \{C. Roland\} and Roberts, \{Gordon, C.K.\}",

year = "2008",

month = oct,

doi = "10.1124/dmd.108.021733",

language = "English",

volume = "36",

pages = "2136--2144",

journal = "Drug Metabolism and Disposition",

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T1 - Multiple substrate binding by cytochrome P450 3A4

T2 - Estimation of the number of bound substrate molecules

AU - Kapelyukh, Yury

AU - Paine, Mark, J.I.

AU - Mar├®chal, Jean-Didier

AU - Sutcliffe, Michael, J.

AU - Wolf, C. Roland

AU - Roberts, Gordon, C.K.

PY - 2008/10

Y1 - 2008/10

KW - Chemistry

U2 - 10.1124/dmd.108.021733

DO - 10.1124/dmd.108.021733

M3 - Article

SN - 0090-9556

VL - 36

SP - 2136

EP - 2144

JO - Drug Metabolism and Disposition

JF - Drug Metabolism and Disposition

IS - 10

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