NAD(P)H: Quinone oxidoreductase-1 C609T polymorphism analysis in human superficial bladder cancers; relationship of genotype status to NQO1 phenotype and clinical response to mitomycin C

Saurajyoti Basu; John E. Brown; G. Michael Flannigan; Jason H. Gill; Paul M. Loadman; Sandie W. Martin; Brian Naylor; Rajiv Puri; Andrew J. Scally; Jill M. Seargent; Tariq Shah; Roger M. Phillips

NAD(P)H: Quinone oxidoreductase-1 C609T polymorphism analysis in human superficial bladder cancers; relationship of genotype status to NQO1 phenotype and clinical response to mitomycin C

Saurajyoti Basu
, John E. Brown
, G. Michael Flannigan
, Jason H. Gill
, Paul M. Loadman
, Sandie W. Martin
, Brian Naylor
, Rajiv Puri
, Andrew J. Scally
, Jill M. Seargent
, Tariq Shah
, Roger M. Phillips

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	921-928
Journal	International Journal of Oncology
Volume	25
Issue number	4
Publication status	Published - Oct 2004
Externally published	Yes

Keywords

mitomycin c
nqo1
bladder cancer
polymorphism
dt-diaphorase activity
bioreductive drug development
tumor-cell-line
human colon
cytochrome-p450 reductase
metabolic-activation
gene-expression
dna-damage
carcinoma
nad(p)h
Chemistry

Access to Document

http://www.spandidos-publications.com/ijo/25/4/921

Cite this

Basu, S., Brown, J. E., Flannigan, G. M., Gill, J. H., Loadman, P. M., Martin, S. W., Naylor, B., Puri, R., Scally, A. J., Seargent, J. M., Shah, T., & Phillips, R. M. (2004). NAD(P)H: Quinone oxidoreductase-1 C609T polymorphism analysis in human superficial bladder cancers; relationship of genotype status to NQO1 phenotype and clinical response to mitomycin C. International Journal of Oncology, 25(4), 921-928. http://www.spandidos-publications.com/ijo/25/4/921

@article{5f50f46c0b484770a766738ca1d3df20,

title = "NAD(P)H: Quinone oxidoreductase-1 C609T polymorphism analysis in human superficial bladder cancers; relationship of genotype status to NQO1 phenotype and clinical response to mitomycin C",

keywords = "mitomycin c, nqo1, bladder cancer, polymorphism, dt-diaphorase activity, bioreductive drug development, tumor-cell-line, human colon, cytochrome-p450 reductase, metabolic-activation, gene-expression, dna-damage, carcinoma, nad(p)h, Chemistry",

author = "Saurajyoti Basu and Brown, \{John E.\} and Flannigan, \{G. Michael\} and Gill, \{Jason H.\} and Loadman, \{Paul M.\} and Martin, \{Sandie W.\} and Brian Naylor and Rajiv Puri and Scally, \{Andrew J.\} and Seargent, \{Jill M.\} and Tariq Shah and Phillips, \{Roger M.\}",

year = "2004",

month = oct,

language = "English",

volume = "25",

pages = "921--928",

journal = "International Journal of Oncology",

issn = "1019-6439",

publisher = "Spandidos Publications",

number = "4",

}

Basu, S, Brown, JE, Flannigan, GM, Gill, JH, Loadman, PM, Martin, SW, Naylor, B, Puri, R, Scally, AJ, Seargent, JM, Shah, T & Phillips, RM 2004, 'NAD(P)H: Quinone oxidoreductase-1 C609T polymorphism analysis in human superficial bladder cancers; relationship of genotype status to NQO1 phenotype and clinical response to mitomycin C', International Journal of Oncology, vol. 25, no. 4, pp. 921-928. <http://www.spandidos-publications.com/ijo/25/4/921>

NAD(P)H: Quinone oxidoreductase-1 C609T polymorphism analysis in human superficial bladder cancers; relationship of genotype status to NQO1 phenotype and clinical response to mitomycin C. / Basu, Saurajyoti; Brown, John E.; Flannigan, G. Michael et al.
In: International Journal of Oncology, Vol. 25, No. 4, 10.2004, p. 921-928.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - NAD(P)H

T2 - Quinone oxidoreductase-1 C609T polymorphism analysis in human superficial bladder cancers; relationship of genotype status to NQO1 phenotype and clinical response to mitomycin C

AU - Basu, Saurajyoti

AU - Brown, John E.

AU - Flannigan, G. Michael

AU - Gill, Jason H.

AU - Loadman, Paul M.

AU - Martin, Sandie W.

AU - Naylor, Brian

AU - Puri, Rajiv

AU - Scally, Andrew J.

AU - Seargent, Jill M.

AU - Shah, Tariq

AU - Phillips, Roger M.

PY - 2004/10

Y1 - 2004/10

KW - mitomycin c

KW - nqo1

KW - bladder cancer

KW - polymorphism

KW - dt-diaphorase activity

KW - bioreductive drug development

KW - tumor-cell-line

KW - human colon

KW - cytochrome-p450 reductase

KW - metabolic-activation

KW - gene-expression

KW - dna-damage

KW - carcinoma

KW - nad(p)h

KW - Chemistry

M3 - Article

SN - 1019-6439

VL - 25

SP - 921

EP - 928

JO - International Journal of Oncology

JF - International Journal of Oncology

IS - 4

ER -