Polymorphisms in the apolipoprotein L1 gene and their effects on blood lipid and glucose levels in middle age males.

Nigel Page; Estibaliz Olano-Martin; Christopher Lanaway; Rufus Turner; Anne Marie Minihane

doi:10.1007/BF02829955

Polymorphisms in the apolipoprotein L1 gene and their effects on blood lipid and glucose levels in middle age males.

Nigel Page
, Estibaliz Olano-Martin
, Christopher Lanaway
, Rufus Turner
, Anne Marie Minihane

Research output: Contribution to journal › Article › peer-review

Abstract

Apolipoprotein L1 in plasma is associated with high-density lipoprotein. Novel APOL1 polymorphisms are investigated along with the association of two common haplotypes (Lysl66Glu, Ile244Met, Lys271Arg) with circulating lipid and glucose levels. Although the amino acid substitutions occur in the amphipathic alpha helices region involved in lipid binding, these substitutions were found not to independently account for variability in circulating lipid and glucose levels in 149 middle age males.

Original language	English
Pages (from-to)	133-136
Journal	Genes and Nutrition
Volume	1
Issue number	2
DOIs	https://doi.org/10.1007/BF02829955
Publication status	Published - 2006

Keywords

Biological sciences

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10.1007/BF02829955

http://dx.doi.org/10.1007/BF02829955

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title = "Polymorphisms in the apolipoprotein L1 gene and their effects on blood lipid and glucose levels in middle age males.",

abstract = "Apolipoprotein L1 in plasma is associated with high-density lipoprotein. Novel APOL1 polymorphisms are investigated along with the association of two common haplotypes (Lysl66Glu, Ile244Met, Lys271Arg) with circulating lipid and glucose levels. Although the amino acid substitutions occur in the amphipathic alpha helices region involved in lipid binding, these substitutions were found not to independently account for variability in circulating lipid and glucose levels in 149 middle age males.",

keywords = "Biological sciences",

author = "Nigel Page and Estibaliz Olano-Martin and Christopher Lanaway and Rufus Turner and Minihane, \{Anne Marie\}",

year = "2006",

doi = "10.1007/BF02829955",

language = "English",

volume = "1",

pages = "133--136",

journal = "Genes and Nutrition",

issn = "1555-8932",

publisher = "BioMed Central Ltd",

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TY - JOUR

T1 - Polymorphisms in the apolipoprotein L1 gene and their effects on blood lipid and glucose levels in middle age males.

AU - Page, Nigel

AU - Olano-Martin, Estibaliz

AU - Lanaway, Christopher

AU - Turner, Rufus

AU - Minihane, Anne Marie

PY - 2006

Y1 - 2006

N2 - Apolipoprotein L1 in plasma is associated with high-density lipoprotein. Novel APOL1 polymorphisms are investigated along with the association of two common haplotypes (Lysl66Glu, Ile244Met, Lys271Arg) with circulating lipid and glucose levels. Although the amino acid substitutions occur in the amphipathic alpha helices region involved in lipid binding, these substitutions were found not to independently account for variability in circulating lipid and glucose levels in 149 middle age males.

AB - Apolipoprotein L1 in plasma is associated with high-density lipoprotein. Novel APOL1 polymorphisms are investigated along with the association of two common haplotypes (Lysl66Glu, Ile244Met, Lys271Arg) with circulating lipid and glucose levels. Although the amino acid substitutions occur in the amphipathic alpha helices region involved in lipid binding, these substitutions were found not to independently account for variability in circulating lipid and glucose levels in 149 middle age males.

KW - Biological sciences

UR - http://www.springer.com/biomed/human+genetics/journal/12263

U2 - 10.1007/BF02829955

DO - 10.1007/BF02829955

M3 - Article

SN - 1555-8932

VL - 1

SP - 133

EP - 136

JO - Genes and Nutrition

JF - Genes and Nutrition

IS - 2

ER -

Polymorphisms in the apolipoprotein L1 gene and their effects on blood lipid and glucose levels in middle age males.

Abstract

Keywords

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