Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes

Perdita L Pugh; Martin P Vidgeon-Hart; Tracey Ashmeade; Ainsley A Culbert; Zoe Seymour; Marion J Perren; Flora Joyce; Simon T Bate; Anna Babin; David J Virley; Jill C Richardson; Neil Upton; David Sunter

doi:10.1186/1742-2094-4-8

Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes

Perdita L Pugh
, Martin P Vidgeon-Hart
, Tracey Ashmeade
, Ainsley A Culbert
, Zoe Seymour
, Marion J Perren
, Flora Joyce
, Simon T Bate
, Anna Babin
, David J Virley
, Jill C Richardson
, Neil Upton
, David Sunter

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Journal of Neuroinflammation
Volume	4
Issue number	1
DOIs	https://doi.org/10.1186/1742-2094-4-8
Publication status	Published - 26 Feb 2007

Keywords

Biological sciences

Access to Document

10.1186/1742-2094-4-8

https://doi.org/10.1186/1742-2094-4-8

Cite this

Pugh, P. L., Vidgeon-Hart, M. P., Ashmeade, T., Culbert, A. A., Seymour, Z., Perren, M. J., Joyce, F., Bate, S. T., Babin, A., Virley, D. J., Richardson, J. C., Upton, N., & Sunter, D. (2007). Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes. Journal of Neuroinflammation, 4(1). https://doi.org/10.1186/1742-2094-4-8

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title = "Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes",

keywords = "Biological sciences",

author = "Pugh, \{Perdita L\} and Vidgeon-Hart, \{Martin P\} and Tracey Ashmeade and Culbert, \{Ainsley A\} and Zoe Seymour and Perren, \{Marion J\} and Flora Joyce and Bate, \{Simon T\} and Anna Babin and Virley, \{David J\} and Richardson, \{Jill C\} and Neil Upton and David Sunter",

year = "2007",

month = feb,

day = "26",

doi = "10.1186/1742-2094-4-8",

language = "English",

volume = "4",

journal = "Journal of Neuroinflammation",

issn = "1742-2094",

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Pugh, PL, Vidgeon-Hart, MP, Ashmeade, T, Culbert, AA, Seymour, Z, Perren, MJ, Joyce, F, Bate, ST, Babin, A, Virley, DJ, Richardson, JC, Upton, N & Sunter, D 2007, 'Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes', Journal of Neuroinflammation, vol. 4, no. 1. https://doi.org/10.1186/1742-2094-4-8

Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes. / Pugh, Perdita L; Vidgeon-Hart, Martin P; Ashmeade, Tracey et al.
In: Journal of Neuroinflammation, Vol. 4, No. 1, 26.02.2007.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes

AU - Pugh, Perdita L

AU - Vidgeon-Hart, Martin P

AU - Ashmeade, Tracey

AU - Culbert, Ainsley A

AU - Seymour, Zoe

AU - Perren, Marion J

AU - Joyce, Flora

AU - Bate, Simon T

AU - Babin, Anna

AU - Virley, David J

AU - Richardson, Jill C

AU - Upton, Neil

AU - Sunter, David

PY - 2007/2/26

Y1 - 2007/2/26

KW - Biological sciences

U2 - 10.1186/1742-2094-4-8

DO - 10.1186/1742-2094-4-8

M3 - Article

SN - 1742-2094

VL - 4

JO - Journal of Neuroinflammation

JF - Journal of Neuroinflammation

IS - 1

ER -

Pugh PL, Vidgeon-Hart MP, Ashmeade T, Culbert AA, Seymour Z, Perren MJ et al. Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes. Journal of Neuroinflammation. 2007 Feb 26;4(1). doi: 10.1186/1742-2094-4-8