Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue

Jonathan Green; Ryan A.J. Tinson; Jacob H.J. Betts; Monica Piras; Aylin Pelut; Dietmar Steverding; Stephen P. Wren; Mark Searcey; Linda Troeberg

doi:10.1016/j.bmc.2023.117424

Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue

Jonathan Green, Ryan A.J. Tinson, Jacob H.J. Betts, Monica Piras, Aylin Pelut, Dietmar Steverding, Stephen P. Wren, Mark Searcey, Linda Troeberg

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	117424
Journal	Bioorganic and Medicinal Chemistry
Volume	92
Early online date	26 Jul 2023
DOIs	https://doi.org/10.1016/j.bmc.2023.117424
Publication status	Published - 7 Sept 2023

Bibliographical note

Note: This work was supported by Versus Arthritis [grant number 21776].

Keywords

Biological sciences

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10.1016/j.bmc.2023.117424

Wren-S-54241-VoRFinal published version, 3.55 MBLicence: CC BY

https://doi.org/10.1016/j.bmc.2023.117424

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Green, J., Tinson, R. A. J., Betts, J. H. J., Piras, M., Pelut, A., Steverding, D., Wren, S. P., Searcey, M., & Troeberg, L. (2023). Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue. Bioorganic and Medicinal Chemistry, 92, Article 117424. https://doi.org/10.1016/j.bmc.2023.117424

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title = "Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue",

keywords = "Biological sciences",

author = "Jonathan Green and Tinson, \{Ryan A.J.\} and Betts, \{Jacob H.J.\} and Monica Piras and Aylin Pelut and Dietmar Steverding and Wren, \{Stephen P.\} and Mark Searcey and Linda Troeberg",

note = "Note: This work was supported by Versus Arthritis [grant number 21776].",

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doi = "10.1016/j.bmc.2023.117424",

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T1 - Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue

AU - Green, Jonathan

AU - Tinson, Ryan A.J.

AU - Betts, Jacob H.J.

AU - Piras, Monica

AU - Pelut, Aylin

AU - Steverding, Dietmar

AU - Wren, Stephen P.

AU - Searcey, Mark

AU - Troeberg, Linda

N1 - Note: This work was supported by Versus Arthritis [grant number 21776].

PY - 2023/9/7

Y1 - 2023/9/7

KW - Biological sciences

UR - https://www.sciencedirect.com/journal/bioorganic-and-medicinal-chemistry

U2 - 10.1016/j.bmc.2023.117424

DO - 10.1016/j.bmc.2023.117424

M3 - Article

SN - 0968-0896

VL - 92

JO - Bioorganic and Medicinal Chemistry

JF - Bioorganic and Medicinal Chemistry

M1 - 117424

ER -

Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue

Bibliographical note

Keywords

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