Suramin inhibits osteoarthritic cartilage degradation by increasing extracellular levels of chondroprotective tissue inhibitor of metalloproteinases 3

Anastasios Chanalaris; Christine Doherty; Brian D. Marsden; Gabriel Bambridge; Stephen P. Wren; Hideaki Nagase; Linda Troeberg

doi:10.1124/mol.117.109397

Suramin inhibits osteoarthritic cartilage degradation by increasing extracellular levels of chondroprotective tissue inhibitor of metalloproteinases 3

Anastasios Chanalaris
, Christine Doherty
, Brian D. Marsden
, Gabriel Bambridge
, Stephen P. Wren
, Hideaki Nagase
, Linda Troeberg

University of Oxford

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	459-468
Journal	Molecular Pharmacology
Volume	92
Issue number	4
DOIs	https://doi.org/10.1124/mol.117.109397
Publication status	Published - 1 Oct 2017

Bibliographical note

Note: The work was supported by Arthritis Research UK [Grants 19466, 20205, and 20887], the Kennedy Trust for Rheumatology Research, and the National Institutes of Health National Institute of Arthritis and Musculoskeletal and Skin Diseases [Grant RO1 AR40994].

Keywords

Chemistry

Access to Document

10.1124/mol.117.109397

Wren-S-P-47394-VoRFinal published version, 1.06 MBLicence: CC BY

https://doi.org/10.1124/mol.117.109397

Cite this

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title = "Suramin inhibits osteoarthritic cartilage degradation by increasing extracellular levels of chondroprotective tissue inhibitor of metalloproteinases 3",

keywords = "Chemistry",

author = "Anastasios Chanalaris and Christine Doherty and Marsden, \{Brian D.\} and Gabriel Bambridge and Wren, \{Stephen P.\} and Hideaki Nagase and Linda Troeberg",

note = "Note: The work was supported by Arthritis Research UK [Grants 19466, 20205, and 20887], the Kennedy Trust for Rheumatology Research, and the National Institutes of Health National Institute of Arthritis and Musculoskeletal and Skin Diseases [Grant RO1 AR40994].",

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AU - Chanalaris, Anastasios

AU - Doherty, Christine

AU - Marsden, Brian D.

AU - Bambridge, Gabriel

AU - Wren, Stephen P.

AU - Nagase, Hideaki

AU - Troeberg, Linda

N1 - Note: The work was supported by Arthritis Research UK [Grants 19466, 20205, and 20887], the Kennedy Trust for Rheumatology Research, and the National Institutes of Health National Institute of Arthritis and Musculoskeletal and Skin Diseases [Grant RO1 AR40994].

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DO - 10.1124/mol.117.109397

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JO - Molecular Pharmacology

JF - Molecular Pharmacology

IS - 4

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