Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-substituted phenyl alkyl triazole-based compounds as potential inhibitors of 17 alpha-hydroxylase/17,20-lyase (P450(17 alpha))

Caroline Owen; Sachin Dhanani; Chirag Patel; Sabbir Ahmed

doi:10.2174/157018007781788471

Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-substituted phenyl alkyl triazole-based compounds as potential inhibitors of 17 alpha-hydroxylase/17,20-lyase (P450(17 alpha))

Caroline Owen
, Sachin Dhanani
, Chirag Patel
, Sabbir Ahmed

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	479-483
Journal	Letters in Drug Design and Discovery
Volume	4
Issue number	7
DOIs	https://doi.org/10.2174/157018007781788471
Publication status	Published - Oct 2007
Externally published	Yes

Keywords

17 alpha-hydroxylase
17
20-lyase
p450(17 alpha)
synthesis
evaluation
triazole
cancer
range
Pharmacy

Access to Document

10.2174/157018007781788471

http://dx.doi.org/10.2174/157018007781788471

Cite this

Owen, C., Dhanani, S., Patel, C., & Ahmed, S. (2007). Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-substituted phenyl alkyl triazole-based compounds as potential inhibitors of 17 alpha-hydroxylase/17,20-lyase (P450(17 alpha)). Letters in Drug Design and Discovery, 4(7), 479-483. https://doi.org/10.2174/157018007781788471

@article{60770eeb1f2244328cd413617aa776d2,

title = "Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-substituted phenyl alkyl triazole-based compounds as potential inhibitors of 17 alpha-hydroxylase/17,20-lyase (P450(17 alpha))",

keywords = "17 alpha-hydroxylase, 17, 20-lyase, p450(17 alpha), synthesis, evaluation, triazole, cancer, range, Pharmacy",

author = "Caroline Owen and Sachin Dhanani and Chirag Patel and Sabbir Ahmed",

year = "2007",

month = oct,

doi = "10.2174/157018007781788471",

language = "English",

volume = "4",

pages = "479--483",

journal = "Letters in Drug Design and Discovery",

issn = "1570-1808",

publisher = "Bentham Science Publishers",

number = "7",

}

Owen, C, Dhanani, S, Patel, C & Ahmed, S 2007, 'Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-substituted phenyl alkyl triazole-based compounds as potential inhibitors of 17 alpha-hydroxylase/17,20-lyase (P450(17 alpha))', Letters in Drug Design and Discovery, vol. 4, no. 7, pp. 479-483. https://doi.org/10.2174/157018007781788471

Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-substituted phenyl alkyl triazole-based compounds as potential inhibitors of 17 alpha-hydroxylase/17,20-lyase (P450(17 alpha)). / Owen, Caroline; Dhanani, Sachin; Patel, Chirag et al.
In: Letters in Drug Design and Discovery, Vol. 4, No. 7, 10.2007, p. 479-483.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-substituted phenyl alkyl triazole-based compounds as potential inhibitors of 17 alpha-hydroxylase/17,20-lyase (P450(17 alpha))

AU - Owen, Caroline

AU - Dhanani, Sachin

AU - Patel, Chirag

AU - Ahmed, Sabbir

PY - 2007/10

Y1 - 2007/10

KW - 17 alpha-hydroxylase

KW - 17

KW - 20-lyase

KW - p450(17 alpha)

KW - synthesis

KW - evaluation

KW - triazole

KW - cancer

KW - range

KW - Pharmacy

U2 - 10.2174/157018007781788471

DO - 10.2174/157018007781788471

M3 - Article

SN - 1570-1808

VL - 4

SP - 479

EP - 483

JO - Letters in Drug Design and Discovery

JF - Letters in Drug Design and Discovery

IS - 7

ER -