The role of granulocyte-colony stimulating factor biosimilars for supportive cancer care: a year in review

Hannah Moir

    Research output: Contribution to journalArticlepeer-review

    Abstract

    This year-in-review article provides insights into clinical updates relating to granulocyte-colony stimulating factor (G-CSF) biosimilars research presented at five key congresses in 2022. These include the American Society of Clinical Oncology (ASCO) 55th Annual Meeting (3rd-7th June 2022, Chicago, Illinois, USA), European Society for Medical Oncology (ESMO) Congress (9th-13th September 2022, Paris, France), ESMO Asia Congress (2nd-4th December 2022, Singapore), San Antonio Breast Cancer Symposium (SABCS; 6th-10th December 2022, Texas, USA), and American Society of Hematology (ASH) 64th Annual Meeting and Exposition (10th-13th December 2022, New Orleans, Louisiana, USA). Alongside reviewing the current research presented at these key congresses, with a focus on the use of G-CSF agents and biosimilars in patients undergoing treatment for breast, colorectal, and gynaecological cancers, this article provides an overview of current guidelines on the use of G-CSF in supportive cancer care to manage chemotherapy-induced febrile neutropenia and explores trends in G-CSF biosimilars research.
    Original languageEnglish
    Pages (from-to)16-24
    JournalEMJ
    Volume8
    Issue number1
    Early online date16 Mar 2023
    DOIs
    Publication statusPublished - 31 Mar 2023

    Keywords

    • Allied health professions and studies
    • G-CSF biosimilar
    • breast cancer
    • chemotherapy
    • colorectal cancer
    • febrile neutropenia
    • filgrastim
    • granulocyte-colony stimulating factor (G-CSF)
    • gynaecological cancer
    • pegfilgrastim
    • primary prophylaxis

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