The role of microbial genomics in delivering the UK’s national action plan for confronting antimicrobial resistance 2024–29

Tess Johnson; Lewis C.E. Mason; Hayley J. Wilson; James R. Price; Katie L. Hopkins; Marie Anne Chattaway; Alistair Leanord; Olga Francino Marti; Rivie Mayele-Tamina; Stephanie Johnson; Paul Flowers; Willem van Schaik; Kate S. Baker

doi:10.1016/j.lanmic.2026.101372

The role of microbial genomics in delivering the UK’s national action plan for confronting antimicrobial resistance 2024–29

Tess Johnson
, Lewis C.E. Mason
, Hayley J. Wilson
, James R. Price
, Katie L. Hopkins
, Marie Anne Chattaway
, Alistair Leanord
, Olga Francino Marti
, Rivie Mayele-Tamina
, Stephanie Johnson
, Paul Flowers
, Willem van Schaik
, Kate S. Baker

University of Oxford
University of Liverpool
University of Cambridge
University of Warwick
Foundation for Genomics and Population Health
Brighton & Sussex Medical School
UK Health Security Agency
University of Birmingham
University of Glasgow
Autonomous University of Barcelona
University of Strathclyde

Research output: Contribution to journal › Article › peer-review

Abstract

Antimicrobial resistance (AMR) is a major threat to human and animal health, in addition to environmental resilience. Countries set the agenda on their national action against AMR in the form of National Action Plans (NAPs), with the UK’s latest NAP released in May, 2024. Advances in genomics have strengthened our ability to work towards NAP priorities; however, to date, no mapping of the role genomics plays in contributing to specific goals within the NAP has been undertaken. The UK Research and Innovation-funded Transdisciplinary Antimicrobial Resistance Genomics Network brought together a range of stakeholders to discuss the role of genomics for action on AMR and to deliver policy priority-led research, as outlined in the UK NAP 2024–29. We report our discussions in this Personal View, with key roles for genomics, including informing targeted stewardship in health-care settings, supporting AMR literacy, and supporting effective antimicrobial innovation. However, changes in infrastructure, communication, and cross-sector coordination are needed to support implementation.

Original language	English
Article number	101372
Journal	The Lancet Microbe
DOIs	https://doi.org/10.1016/j.lanmic.2026.101372
Publication status	E-pub ahead of print - 4 Mar 2026
Externally published	Yes

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Johnson, T., Mason, L. C. E., Wilson, H. J., Price, J. R., Hopkins, K. L., Chattaway, M. A., Leanord, A., Francino Marti, O., Mayele-Tamina, R., Johnson, S., Flowers, P., van Schaik, W., & Baker, K. S. (2026). The role of microbial genomics in delivering the UK’s national action plan for confronting antimicrobial resistance 2024–29. The Lancet Microbe, Article 101372. Advance online publication. https://doi.org/10.1016/j.lanmic.2026.101372

@article{d77edfdd26334c8e8e6cdbe4479916f1,

title = "The role of microbial genomics in delivering the UK{\textquoteright}s national action plan for confronting antimicrobial resistance 2024–29",

abstract = "Antimicrobial resistance (AMR) is a major threat to human and animal health, in addition to environmental resilience. Countries set the agenda on their national action against AMR in the form of National Action Plans (NAPs), with the UK{\textquoteright}s latest NAP released in May, 2024. Advances in genomics have strengthened our ability to work towards NAP priorities; however, to date, no mapping of the role genomics plays in contributing to specific goals within the NAP has been undertaken. The UK Research and Innovation-funded Transdisciplinary Antimicrobial Resistance Genomics Network brought together a range of stakeholders to discuss the role of genomics for action on AMR and to deliver policy priority-led research, as outlined in the UK NAP 2024–29. We report our discussions in this Personal View, with key roles for genomics, including informing targeted stewardship in health-care settings, supporting AMR literacy, and supporting effective antimicrobial innovation. However, changes in infrastructure, communication, and cross-sector coordination are needed to support implementation.",

author = "Tess Johnson and Mason, \{Lewis C.E.\} and Wilson, \{Hayley J.\} and Price, \{James R.\} and Hopkins, \{Katie L.\} and Chattaway, \{Marie Anne\} and Alistair Leanord and \{Francino Marti\}, Olga and Rivie Mayele-Tamina and Stephanie Johnson and Paul Flowers and \{van Schaik\}, Willem and Baker, \{Kate S.\}",

year = "2026",

month = mar,

day = "4",

doi = "10.1016/j.lanmic.2026.101372",

language = "English",

journal = "The Lancet Microbe",

issn = "2666-5247",

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Johnson, T, Mason, LCE, Wilson, HJ, Price, JR, Hopkins, KL, Chattaway, MA, Leanord, A, Francino Marti, O, Mayele-Tamina, R, Johnson, S, Flowers, P, van Schaik, W & Baker, KS 2026, 'The role of microbial genomics in delivering the UK’s national action plan for confronting antimicrobial resistance 2024–29', The Lancet Microbe. https://doi.org/10.1016/j.lanmic.2026.101372

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T1 - The role of microbial genomics in delivering the UK’s national action plan for confronting antimicrobial resistance 2024–29

AU - Johnson, Tess

AU - Mason, Lewis C.E.

AU - Wilson, Hayley J.

AU - Price, James R.

AU - Hopkins, Katie L.

AU - Chattaway, Marie Anne

AU - Leanord, Alistair

AU - Francino Marti, Olga

AU - Mayele-Tamina, Rivie

AU - Johnson, Stephanie

AU - Flowers, Paul

AU - van Schaik, Willem

AU - Baker, Kate S.

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N2 - Antimicrobial resistance (AMR) is a major threat to human and animal health, in addition to environmental resilience. Countries set the agenda on their national action against AMR in the form of National Action Plans (NAPs), with the UK’s latest NAP released in May, 2024. Advances in genomics have strengthened our ability to work towards NAP priorities; however, to date, no mapping of the role genomics plays in contributing to specific goals within the NAP has been undertaken. The UK Research and Innovation-funded Transdisciplinary Antimicrobial Resistance Genomics Network brought together a range of stakeholders to discuss the role of genomics for action on AMR and to deliver policy priority-led research, as outlined in the UK NAP 2024–29. We report our discussions in this Personal View, with key roles for genomics, including informing targeted stewardship in health-care settings, supporting AMR literacy, and supporting effective antimicrobial innovation. However, changes in infrastructure, communication, and cross-sector coordination are needed to support implementation.

AB - Antimicrobial resistance (AMR) is a major threat to human and animal health, in addition to environmental resilience. Countries set the agenda on their national action against AMR in the form of National Action Plans (NAPs), with the UK’s latest NAP released in May, 2024. Advances in genomics have strengthened our ability to work towards NAP priorities; however, to date, no mapping of the role genomics plays in contributing to specific goals within the NAP has been undertaken. The UK Research and Innovation-funded Transdisciplinary Antimicrobial Resistance Genomics Network brought together a range of stakeholders to discuss the role of genomics for action on AMR and to deliver policy priority-led research, as outlined in the UK NAP 2024–29. We report our discussions in this Personal View, with key roles for genomics, including informing targeted stewardship in health-care settings, supporting AMR literacy, and supporting effective antimicrobial innovation. However, changes in infrastructure, communication, and cross-sector coordination are needed to support implementation.

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DO - 10.1016/j.lanmic.2026.101372

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SN - 2666-5247

JO - The Lancet Microbe

JF - The Lancet Microbe

M1 - 101372

ER -

The role of microbial genomics in delivering the UK’s national action plan for confronting antimicrobial resistance 2024–29

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