TY - JOUR
T1 - Treatment plan comparison in acute and chronic respiratory tract diseases
T2 - an observational study of doxophylline vs. theophylline
AU - Mennini, F. S.
AU - Sciattella, P.
AU - Marcellusi, A.
AU - Marcobelli, A.
AU - Russo, A.
AU - Caputi, A. P.
PY - 2017
Y1 - 2017
N2 - BACKGROUND:
The main objective of this article is to estimate the global cost related to the use of the two drugs (associated drugs, specialist visits, hospital admissions, plasma drug monitoring).
METHODS:
The drug prescriptions were extracted from the Information System of the Pharmaceutical Prescriptions of the Marche Region for each ATC code in the years 2008-2012 and the number of patients per year and other outcomes measure were obtained.
RESULTS:
13,574 patients were treated with theophylline and 19,426 patients with doxophylline. The number of patients treated was approximately 5,000 per year. Co-prescription with other drugs, use of corticosteroids, mean number of visits and hospital admissions (per 100 patients) were lower for doxophylline vs theophylline (1.55vs5.50, 0.3vs0.7, 2.05vs3.73 and 1.57vs3.3 respectively). The annual mean cost per patient was €187.4 for those treated with doxophylline and €513.5 for theophylline.
CONCLUSIONS:
In our study, doxophylline resulted to be associated with a reduction of the overall cost.
AB - BACKGROUND:
The main objective of this article is to estimate the global cost related to the use of the two drugs (associated drugs, specialist visits, hospital admissions, plasma drug monitoring).
METHODS:
The drug prescriptions were extracted from the Information System of the Pharmaceutical Prescriptions of the Marche Region for each ATC code in the years 2008-2012 and the number of patients per year and other outcomes measure were obtained.
RESULTS:
13,574 patients were treated with theophylline and 19,426 patients with doxophylline. The number of patients treated was approximately 5,000 per year. Co-prescription with other drugs, use of corticosteroids, mean number of visits and hospital admissions (per 100 patients) were lower for doxophylline vs theophylline (1.55vs5.50, 0.3vs0.7, 2.05vs3.73 and 1.57vs3.3 respectively). The annual mean cost per patient was €187.4 for those treated with doxophylline and €513.5 for theophylline.
CONCLUSIONS:
In our study, doxophylline resulted to be associated with a reduction of the overall cost.
KW - Epidemiology and public health
UR - https://www.ncbi.nlm.nih.gov/pubmed/28277853
U2 - 10.1080/14737167.2017.1301815
DO - 10.1080/14737167.2017.1301815
M3 - Article
C2 - 28277853
SN - 1475-3634
VL - 17
SP - 503
EP - 510
JO - Psychodynamic Practice
JF - Psychodynamic Practice
IS - 5
ER -